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New experimental therapy shows safety and signals New experimental therapy shows safety and signals of clinical benefit in ALS patients.

The investigational therapy, PrimeC, has shown safety and early signals of clinical benefit in people living with ALS. The findings come from the PARADIGM study, led by teams from @massgeneralbrigham Neuroscience Institute and Barrow Neurological Institute and @harvardmed.

ALS is a progressive neurodegenerative disease that leads to muscle weakness and loss of motor function. PrimeC, an oral therapy, targets multiple processes that contribute to ALS progression.

“The importance of following up on potential therapies that can slow the course of ALS is extraordinarily high for patients and families," said study author Merit Cudkowicz, MD, MSc. "We are determined to accelerate the development of therapies for people living with ALS."

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