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According to a new study, a hormone created during According to a new study, a hormone created during exercise could offer neuroprotective effects in multiple sclerosis (MS). In this image, the scientists identified that the exercise hormone irisin (yellow) binds to spinal cord neurons (magenta) in their experimental model of MS. They found that irisin reduced both clinical symptoms and the loss of neurons. Additionally, when irisin was removed from the model, the protective effects of exercise disappeared. Taken together, the researchers’ findings suggest that irisin can protect neurons from inflammation-driven neurodegeneration, offering a potential target for future MS therapies. “We are optimistic that our study will open up further developments of irisin as a therapeutic for, in particular, progressive MS,” said author Christiane D. Wrann, DVM, PhD. “Our findings strengthen the argument that irisin can help protect neurons in the context of multiple types of neurodegenerative diseases.” (Image credit to Sina Rosenkranz).

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